Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690728 | 0.90 | ALDH1A1 (0.32) | SPHK2TNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL10392875 | 0.85 | VDR (0.31) | VDRPPARA | |
| SCHEMBL9813447 | 0.79 | PPARA (0.38) | SPHK2TNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL9700881 | 0.76 | S1PR2 (0.31) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL10394793 | 0.75 | CYP3A4 (0.32) | ALDH1A1 | |
| SCHEMBL9813462 | 0.74 | THRA (0.32) | SPHK2TNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL10693312 | 0.74 | SPHK2 (0.31) | SPHK2TNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL9700639 | 0.72 | ALDH1A1 (0.35) | ALDH1A1HTT | |
| SCHEMBL9813439 | 0.71 | TAAR1 (0.35) | ALDH1A1PPARA | |
| SCHEMBL9813438 | 0.71 | MEN1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783473-A | ANTICOAGULANTS, VASODILATORS, BRONCHODILATORS | E. R. SQUIBB & SONS, INC. (US) | 1988-11-08 | — | — | US | disclosed |