Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240599 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1USP2GAAMAPT | |
| SCHEMBL29420723 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1USP2GAAMAPT | |
| SCHEMBL5749182 | 0.77 | ALDH1A1 (0.44) | KDM4EALDH1A1USP2GAAMAPT | |
| SCHEMBL31588139 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL11324492 | 0.74 | TSHR (0.48) | KDM4EALDH1A1USP2GAAMAPT | |
| SCHEMBL5747311 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1USP2GAAMAPT | |
| SCHEMBL5750565 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1USP2GAAMAPT | |
| SCHEMBL630084 | 0.73 | IMPDH2 (0.52) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL2028221 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1USP2GAAMAPT | |
| SCHEMBL819997 | 0.72 | CA1 (0.52) | KDM4EALDH1A1GAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792508-A | STEREOISOMERIC NAPHTHALENE IMIDAZOLE PERYLENES, ARYL AMINES | XEROX CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |