Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694742 | 0.78 | MEN1 (0.45) | MEN1KMT2AL3MBTL1PKMNPSR1 | |
| SCHEMBL10690529 | 0.78 | KMT2A (0.53) | MEN1KMT2AL3MBTL1PKMCYP1A2 | |
| SCHEMBL10694737 | 0.77 | MEN1 (0.52) | MEN1KMT2AL3MBTL1PKMNPSR1 | |
| SCHEMBL10696078 | 0.73 | ALDH1A1 (0.49) | MEN1KMT2AL3MBTL1PKMNPSR1 | |
| SCHEMBL7671680 | 0.73 | KMT2A (0.51) | MEN1KMT2AL3MBTL1NPSR1CYP1A2 | |
| SCHEMBL8795412 | 0.71 | SMN1; SMN2 (0.58) | MEN1KMT2AL3MBTL1NPSR1SMN1; SMN2 | |
| SCHEMBL619782 | 0.71 | ADORA3 (0.52) | MEN1KMT2APPARDPPARA | |
| SCHEMBL10933583 | 0.69 | ADORA3 (0.46) | ALDH1A1PPARDPPARALMNA | |
| SCHEMBL3500736 | 0.69 | PPARA (0.68) | MEN1KMT2ANPSR1CYP1A2CYP2C19 | |
| SCHEMBL3672006 | 0.68 | SMN1; SMN2 (0.66) | MEN1KMT2ANPSR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753673-A | GRASSY WEEDS | THE DOW CHEMICAL COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| US-4628099-A | INTERMEDIATES FOR HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1986-12-09 | — | — | US | disclosed |
| US-4551170-A | Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanols and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1985-11-05 | — | — | US | disclosed |
| US-4523017-A | REACTING CHLORIDE SUBSTITUTED PYRIDINE COMPOUND WITH SUBSTITUTED PHENOL COMPOUND | THE DOW CHEMICAL COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4491468-A | Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanenitriles and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4479001-A | Trifluoromethyl pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1984-10-23 | — | — | US | disclosed |