Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | APLNR | P35414 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SDHB | P21912 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363011 | 0.81 | KDM4E (0.41) | MAPTLMNASDHBNOTUMKMT2A | |
| SCHEMBL10696730 | 0.78 | KDM4E (0.48) | MAPTLMNASDHBKMT2AKDM4E | |
| SCHEMBL6730105 | 0.77 | KDM4E (0.43) | MAPTLMNASDHBKMT2AKDM4E | |
| SCHEMBL10364788 | 0.76 | KDM4E (0.38) | MAPTLMNASDHBNOTUMCFTR | |
| SCHEMBL10696362 | 0.75 | ALDH1A1 (0.38) | MAPTLMNAGAAKMT2AKDM4E | |
| SCHEMBL10364438 | 0.74 | MAPT (0.40) | MAPTLMNAGAASDHBNOTUM | |
| SCHEMBL6734856 | 0.74 | CYP3A4 (0.44) | MAPTLMNAGAASDHBNOTUM | |
| SCHEMBL6730092 | 0.73 | LMNA (0.44) | LMNANOTUMKDM4EALDH1A1POLB | |
| SCHEMBL10363915 | 0.73 | ATF1 (0.36) | MAPTLMNAGAASDHBNOTUM | |
| SCHEMBL385370 | 0.72 | LMNA (0.60) | MAPTLMNANOTUMCFTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276204-A2 | Pyridine gametocides | Monsanto Company (US) | 1988-07-27 | — | — | EP | claimed |