Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SDHB | P21912 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | IGF1R | P08069 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730105 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1POLBSDHBMAPT | |
| SCHEMBL10363011 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1POLBSDHBHSD17B10 | |
| SCHEMBL6730092 | 0.79 | LMNA (0.44) | KDM4EALDH1A1POLBLMNAHPGD | |
| SCHEMBL10694814 | 0.78 | MAPT (0.44) | KDM4EALDH1A1POLBSDHBMAPT | |
| SCHEMBL10364788 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1POLBSDHBMAPT | |
| SCHEMBL10696362 | 0.74 | ALDH1A1 (0.38) | KDM4EALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL10364438 | 0.73 | MAPT (0.40) | KDM4EALDH1A1POLBSDHBMAPT | |
| SCHEMBL6734856 | 0.73 | CYP3A4 (0.44) | KDM4EALDH1A1POLBSDHBMAPT | |
| SCHEMBL10698356 | 0.71 | CYP1A2 (0.41) | KDM4EALDH1A1POLBSDHBMAPT | |
| SCHEMBL10363915 | 0.70 | ATF1 (0.36) | KDM4EALDH1A1POLBSDHBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276204-A2 | Pyridine gametocides | Monsanto Company (US) | 1988-07-27 | — | — | EP | claimed |