Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695350 | 0.88 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10CYP1A2SCN8A | |
| SCHEMBL10693012 | 0.87 | HTR1B (0.42) | KDM4EALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL10690950 | 0.84 | HTR1B (0.50) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL10693265 | 0.82 | SLC6A4 (0.49) | KDM4EALDH1A1SCN8A | |
| SCHEMBL10688822 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL10692538 | 0.80 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10CYP1A2SCN8A | |
| SCHEMBL3694800 | 0.79 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10CYP1A2SCN8A | |
| SCHEMBL10691850 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ACYP1A2GAA | |
| SCHEMBL27603617 | 0.77 | CNR1 (0.41) | KDM4EALDH1A1MAPTHSD17B10CYP1A2 | |
| SCHEMBL10694048 | 0.76 | HPGD (0.51) | ALDH1A1MAPTNPSR1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |