Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 11/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694997 | 0.82 | KDM4E (0.40) | SCN8AKDM4EALDH1A1 | |
| SCHEMBL7700722 | 0.81 | SCN8A (0.60) | SLC6A4HRH1HTR1BSCN8AKDM4E | |
| SCHEMBL10693012 | 0.79 | HTR1B (0.42) | SLC6A4HTR1BSCN8AKDM4EALDH1A1 | |
| SCHEMBL10690950 | 0.77 | HTR1B (0.50) | HTR1BKDM4EALDH1A1 | |
| SCHEMBL7697428 | 0.76 | ALDH1A1 (0.63) | SLC6A4HTR1BSCN8AKDM4EALDH1A1 | |
| SCHEMBL5591551 | 0.76 | HTR1B (0.65) | HTR1BSCN8AHTR1DKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2718257 | 0.74 | HTR1B (0.62) | HTR1BSCN8AHTR1DKDM4EALDH1A1 | |
| SCHEMBL3694800 | 0.72 | ALDH1A1 (0.41) | SLC6A4HTR1BSCN8AKDM4EALDH1A1 | |
| SCHEMBL10695350 | 0.72 | ALDH1A1 (0.41) | SLC6A4HRH1HTR1BSCN8AKDM4E | |
| SCHEMBL10691850 | 0.72 | ALDH1A1 (0.63) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |