Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694997 | 0.78 | KDM4E (0.40) | ALDH1A1MEN1CYP1A2KMT2AGAA | |
| SCHEMBL10688459 | 0.78 | HRH3 (0.64) | ALDH1A1CYP2D6MEN1CYP1A2KMT2A | |
| SCHEMBL10693012 | 0.76 | HTR1B (0.42) | ALDH1A1CYP2D6MEN1CYP1A2KMT2A | |
| SCHEMBL10695028 | 0.75 | HRH3 (0.64) | ALDH1A1CYP2D6MEN1CYP1A2KMT2A | |
| SCHEMBL22627295 | 0.75 | ALDH1A1 (0.76) | ALDH1A1CYP2D6MEN1CYP1A2KMT2A | |
| SCHEMBL10694048 | 0.74 | HPGD (0.51) | ALDH1A1CYP2D6CYP1A2KMT2ACYP2C19 | |
| SCHEMBL22610054 | 0.73 | CYP2D6 (0.85) | ALDH1A1CYP2D6MEN1CYP1A2KMT2A | |
| SCHEMBL10690950 | 0.73 | HTR1B (0.50) | ALDH1A1CYP2D6MEN1CYP1A2KMT2A | |
| SCHEMBL24163014 | 0.73 | L3MBTL1 (0.71) | ALDH1A1CYP2D6MEN1CYP1A2KMT2A | |
| SCHEMBL24163023 | 0.72 | HRH3 (0.58) | ALDH1A1MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |