Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698002 | 0.83 | HSD17B10 (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3175500 | 0.80 | NOTUM (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10554028 | 0.76 | NOTUM (0.36) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9723067 | 0.75 | RAPGEF4 (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11713810 | 0.75 | HSD17B10 (0.59) | HSD17B10HPGDTSHRCASP1CYP3A4 | |
| SCHEMBL10695590 | 0.74 | HSD17B10 (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7071048 | 0.73 | IDO1 (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9774981 | 0.71 | LMNA (0.32) | — | |
| SCHEMBL11602223 | 0.69 | NOTUM (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30572960 | 0.68 | EPAS1 (0.35) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |