Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695573 | 0.83 | HTR3E (0.37) | HSD17B10TSHRHPGDMAPK1HTR3E | |
| SCHEMBL10695590 | 0.83 | HSD17B10 (0.52) | HSD17B10TSHRHPGDMAPK1HTR3E | |
| SCHEMBL3175500 | 0.80 | NOTUM (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7894304 | 0.75 | TP53 (0.34) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9748215 | 0.75 | ALDH1A1 (0.36) | TSHRHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11713810 | 0.75 | HSD17B10 (0.59) | HSD17B10TSHRHPGDMAPK1CYP2C19 | |
| SCHEMBL7071048 | 0.73 | IDO1 (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10554028 | 0.71 | NOTUM (0.36) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8530898 | 0.71 | ALDH1A1 (0.32) | TSHRHPGDHIF1AALOX15CYP3A4 | |
| SCHEMBL4431998 | 0.71 | ALDH1A1 (0.32) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |