Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215040 | 0.89 | PIN1 (0.39) | NPBWR1ALDH1A1GAAHPGDGABRP | |
| SCHEMBL9221181 | 0.83 | RECQL (0.41) | ALDH1A1HPGDHTTSMN1; SMN2GABRP | |
| SCHEMBL9215480 | 0.82 | ALDH1A1 (0.38) | NPBWR1ALDH1A1GAAPARP1RAB9A | |
| SCHEMBL9215555 | 0.79 | NPBWR1 (0.38) | NPBWR1ALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL10694101 | 0.79 | PARP1 (0.54) | PARP1RAB9A | |
| SCHEMBL9218118 | 0.78 | NPBWR1 (0.37) | NPBWR1ALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL9705004 | 0.77 | GABRB3 (0.46) | SMN1; SMN2GABRPGABRDNR1I2LMNA | |
| SCHEMBL10697405 | 0.73 | CHEK2 (0.43) | PARP1 | |
| SCHEMBL10697288 | 0.72 | MEN1 (0.48) | NPBWR1GAAPARP1HPGDRPS6KA3 | |
| SCHEMBL10695586 | 0.72 | PARP1 (0.57) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380865-A | Halogen substituents | MAY & BAKER LIMITED (GB) | 1995-01-10 | — | — | US | disclosed |
| US-5206257-A | Controlling plant nematodes, helminth, protozoa | MAY & BAKER LIMITED (GB) | 1993-04-27 | — | — | US | disclosed |
| EP-0283173-A1 | Pesticidal method using 2-phenylimidazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-09-21 | — | — | EP | disclosed |