Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46640 | 0.84 | CA2 (0.56) | MMP12MMP13SIGMAR1SLC6A4MEN1 | |
| SCHEMBL28410098 | 0.83 | MAPT (0.51) | SIGMAR1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9780280 | 0.82 | CYP4F2 (0.46) | SIGMAR1SLC6A4KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6167644 | 0.81 | SLC6A4 (0.46) | MMP12MMP13SLC6A4MEN1KMT2A | |
| SCHEMBL19337318 | 0.81 | SLC6A4 (0.42) | MMP12MMP13SIGMAR1SLC6A4MEN1 | |
| SCHEMBL28228920 | 0.80 | MMP12 (0.49) | MMP12MMP13MEN1KMT2AKDM4E | |
| SCHEMBL7114566 | 0.79 | L3MBTL1 (0.58) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6068538 | 0.78 | ALDH1A1 (0.59) | SLC6A4MEN1KMT2AKDM4EATM | |
| SCHEMBL4869495 | 0.77 | HAO1 (0.53) | MMP12MMP13SIGMAR1SLC6A4MEN1 | |
| Adipic Acid SCHEMBL27542113 | 0.76 | ALDH1A1 (0.49) | MMP12MMP13SIGMAR1SLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |