Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | XPO1 | O14980 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770658 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDTP53HRH3 | |
| SCHEMBL10693610 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDTP53MAPT | |
| SCHEMBL9770496 | 0.74 | CYP1A2 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2TRPV4 | |
| SCHEMBL10696506 | 0.72 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDPDE7APDE4A | |
| SCHEMBL9770688 | 0.71 | ADORA2A (0.39) | ALDH1A1HPGDTP53MAPTSMN1; SMN2 | |
| SCHEMBL10695492 | 0.70 | PARP1 (0.39) | KDM4EALDH1A1HPGDPDE7APDE4A | |
| SCHEMBL15840330 | 0.70 | HRH3 (0.47) | KDM4EXPO1PDE7APDE4APDE4B | |
| SCHEMBL10696499 | 0.69 | PDE7A (0.39) | KDM4EALDH1A1HPGDTP53XPO1 | |
| SCHEMBL9770718 | 0.69 | KDM4E (0.45) | KDM4EALDH1A1HPGDTP53MAPT | |
| SCHEMBL9770716 | 0.67 | PARP1 (0.44) | KDM4EALDH1A1HPGDTP53HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |