Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695797 | 0.71 | KDM4E (0.52) | TRPV4ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL10696499 | 0.71 | PDE7A (0.39) | TRPV4LMNAALDH1A1HPGDRAB9A | |
| SCHEMBL10696506 | 0.71 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL10695759 | 0.69 | CYP1A1 (0.43) | ADORA2AALDH1A1HPGDSMN1; SMN2RXFP1 | |
| SCHEMBL10694328 | 0.68 | ELANE (0.42) | LMNAALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9770629 | 0.68 | TNKS (0.42) | ADORA2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23532121 | 0.66 | MEN1 (0.50) | MEN1KMT2ALMNAMAPK1ALDH1A1 | |
| SCHEMBL10695331 | 0.66 | PDE7A (0.43) | LMNAALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10696216 | 0.66 | PARP1 (0.44) | LMNAGPR139ALDH1A1HPGDRAB9A | |
| SCHEMBL9770496 | 0.65 | CYP1A2 (0.43) | MEN1KMT2ATRPV4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |