Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536458 | 0.86 | NPC1 (0.45) | PDE7ANPC1RAB9AKDM4ELMNA | |
| SCHEMBL9533693 | 0.83 | ELANE (0.40) | PDE7ANPC1RAB9AKDM4ELMNA | |
| SCHEMBL9533817 | 0.80 | TNKS (0.43) | KDM4EHPGDTRPA1AKR1B1PARP1 | |
| SCHEMBL10696981 | 0.78 | PARP1 (0.38) | TRPV4NPC1RAB9AKDM4ELMNA | |
| SCHEMBL10696506 | 0.72 | ALDH1A1 (0.62) | PDE7ANPC1RAB9AKDM4EHPGD | |
| SCHEMBL9770688 | 0.71 | ADORA2A (0.39) | TRPV4NPC1RAB9ALMNATP53 | |
| SCHEMBL10695797 | 0.69 | KDM4E (0.52) | PDE7ATRPV4KDM4ETP53HPGD | |
| SCHEMBL9533229 | 0.69 | PARP1 (0.40) | NPC1RAB9AKDM4ELMNATP53 | |
| SCHEMBL9770496 | 0.69 | CYP1A2 (0.43) | TRPV4KDM4ELMNAHPGDSMN1; SMN2 | |
| SCHEMBL9533044 | 0.67 | ELANE (0.40) | NPC1RAB9AKDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |