Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532194 | 0.86 | KDM4E (0.65) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL9533336 | 0.83 | KDM4E (0.62) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL9536686 | 0.81 | KDM4E (0.59) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL9533007 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL10668697 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| Bromide SCHEMBL11085283 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL10978164 | 0.77 | KDM4E (1.00) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL11084003 | 0.72 | KDM4E (0.66) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL10695797 | 0.72 | KDM4E (0.52) | ALDH1A1HPGDKDM4ESMN1; SMN2PDE4A | |
| SCHEMBL10696499 | 0.72 | PDE7A (0.39) | ALDH1A1HPGDHSD17B10KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |