Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.83 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.72 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755055 | 0.91 | ALOX5 (1.00) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL8652025 | 0.87 | ALOX5 (0.76) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL2353230 | 0.87 | ALOX5 (0.76) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL1957356 | 0.86 | SMN1; SMN2 (0.71) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL8387473 | 0.85 | ALOX5 (0.74) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL339507 | 0.83 | CES2 (0.56) | ALOX5LTB4RLTB4R2 | |
| Iodomethane SCHEMBL8389381 | 0.82 | ALOX5 (0.70) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL10691196 | 0.82 | ALOX5 (0.74) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL68570 | 0.82 | ALOX5 (0.69) | ALOX5LTB4RLTB4R2PTGS1PTGS2 | |
| SCHEMBL10048247 | 0.82 | SMN1; SMN2 (0.66) | ALOX5LTB4RLTB4R2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597238-A | N, the preparation method of N-dimethyl-4-benzyloxy phenyl acetamide | FANPING CAI (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-101223129-A | Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof | WYETH CORP (US) | 2008-07-16 | — | — | CN | claimed |
| EP-1904434-A2 | HIGHLY SELECTIVE SEROTONIN AND NOREPINEPHRINE DUAL REUPTAKE INHIBITOR AND USE THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-04-02 | — | — | EP | claimed |
| WO-2007011594-A2 | HIGHLY SELECTIVE SEROTONIN AND NOREPINEPHRINE DUAL REUPTAKE INHIBITOR AND USE THEREOF | WYETH (US) | 2007-01-25 | — | — | WO | claimed |
| US-20070015828-A1 | Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof | WYETH (US) | 2007-01-18 | — | — | US | claimed |
| US-20160355457-A1 | Solid Forms Comprising(-)-O-Desmethylvenlafaxine And Uses Thereof | SUNOVION PHARMACEUTICALS INC. | 2016-12-08 | — | — | US | disclosed |
| EP-2114863-B1 | SOLID FORMS COMPRISING (-)-O-DESMETHYLVENLAFAXINE AND USES THEREOF | SEPRACOR INC (US) | 2016-10-05 | — | — | EP | disclosed |
| US-20150183722-A1 | Process for the Preparation of O-Desmethyl Venlafaxine and Intermediate for Use Therein | CIPLA LIMITED (IN) | 2015-07-02 | — | — | US | disclosed |
| US-20150183722-A1 | Process for the Preparation of O-Desmethyl Venlafaxine and Intermediate for Use Therein | CIPLA LIMITED (IN) | 2015-07-02 | — | — | US | disclosed |
| US-9012689-B2 | Process for the preparation of O-desmethyl venlafaxine and intermediate for use therein | CIPLA LIMITED (IN) | 2015-04-21 | — | — | US | disclosed |
| US-9012689-B2 | Process for the preparation of O-desmethyl venlafaxine and intermediate for use therein | CIPLA LIMITED (IN) | 2015-04-21 | — | — | US | disclosed |
| EP-2500337-A2 | Solid form comprising (-) o-desmethylvenlafaxine and uses thereof | Sepracor Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| US-20070015828-A1 | Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof | WYETH (US) | 2007-01-18 | — | — | US | disclosed |
| US-20070015828-A1 | Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof | WYETH (US) | 2007-01-18 | — | — | US | disclosed |
| US-20070015828-A1 | Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof | WYETH (US) | 2007-01-18 | — | — | US | disclosed |
| US-20070015791-A1 | Serotonin and norepinephrine reuptake inhibitors and uses thereof | WYETH (US) | 2007-01-18 | — | — | US | disclosed |
| US-20070015791-A1 | Serotonin and norepinephrine reuptake inhibitors and uses thereof | WYETH (US) | 2007-01-18 | — | — | US | disclosed |
| US-20070015791-A1 | Serotonin and norepinephrine reuptake inhibitors and uses thereof | WYETH (US) | 2007-01-18 | — | — | US | disclosed |
| US-20070015824-A1 | Serotonin and norepinephrine reuptake inhibitor and uses thereof | WYETH (US) | 2007-01-18 | — | — | US | disclosed |
| US-20070015824-A1 | Serotonin and norepinephrine reuptake inhibitor and uses thereof | WYETH (US) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015828-A1 | Highly selective serotonin and norepinephrine dual reuptake inhibitor and use thereof | SLC6A2, SLC6A3, SLC6A4 | ALOX5 2019/4885LTB4R 2928/4885LTB4R2 2941/4885 |
| US-20150183722-A1 | Process for the Preparation of O-Desmethyl Venlafaxine and Intermediate for Use Therein | SLC6A2, SLC6A3, MAOA | ALOX5 1190/4885LTB4R 4077/4885LTB4R2 4065/4885 |
| US-20160355457-A1 | Solid Forms Comprising(-)-O-Desmethylvenlafaxine And Uses Thereof | COMT, SLC6A3, SLC6A2 | ALOX5 1567/4885LTB4R 4644/4885LTB4R2 4581/4885 |
| US-20070015791-A1 | Serotonin and norepinephrine reuptake inhibitors and uses thereof | SLC6A2, SLC6A3, SLC6A4 | ALOX5 1659/4885LTB4R 2574/4885LTB4R2 2791/4885 |
| US-20070015824-A1 | Serotonin and norepinephrine reuptake inhibitor and uses thereof | SLC6A2, SLC6A3, SLC6A4 | ALOX5 1872/4885LTB4R 2784/4885LTB4R2 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.