Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 5/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973045 | 0.88 | MTNR1A (0.37) | DYRK1ACLK1DYRK4CYP1A2HTR1A | |
| SCHEMBL10688770 | 0.87 | CYP1A2 (0.42) | HASPINDYRK2DYRK1ADYRK3CLK1 | |
| SCHEMBL10692825 | 0.85 | MAOB (0.46) | HASPINHTR1DHTR6CYP1A2HTR1A | |
| SCHEMBL14884628 | 0.84 | HASPIN (0.55) | HASPINDYRK2DYRK1ADYRK3CLK1 | |
| SCHEMBL10691148 | 0.82 | MAOA (0.49) | CYP1A2MAPT | |
| SCHEMBL10693186 | 0.79 | HTR1B (0.47) | HTR1DNOS3NOS1NOS2CYP1A2 | |
| SCHEMBL10694673 | 0.77 | CYP1A2 (0.44) | HASPINDYRK2DYRK1ADYRK3CLK1 | |
| SCHEMBL10691598 | 0.77 | HPGD (0.50) | HTR1AMAPTTSHRNPSR1 | |
| SCHEMBL2553820 | 0.76 | DYRK3 (0.62) | HASPINDYRK2DYRK1ADYRK3CLK1 | |
| SCHEMBL10693321 | 0.75 | CYP1A2 (0.44) | CYP1A2MAPTHTR2ASLC2A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |