Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695867 | 0.88 | HASPIN (0.40) | MTNR1APLA2G2AMAPTSLC2A1HTR1A | |
| SCHEMBL10693321 | 0.86 | CYP1A2 (0.44) | MTNR1AMTNR1BHPGDL3MBTL1MAPT | |
| SCHEMBL10692825 | 0.86 | MAOB (0.46) | TDP1HTR1ACYP1A2 | |
| SCHEMBL10691148 | 0.83 | MAOA (0.49) | HPGDMAPTACHECYP1A2 | |
| SCHEMBL10691598 | 0.78 | HPGD (0.50) | HPGDL3MBTL1MAPTTDP1LMNA | |
| SCHEMBL10692377 | 0.77 | L3MBTL1 (0.40) | HPGDL3MBTL1MAPTTDP1SLC2A1 | |
| SCHEMBL10688006 | 0.77 | CYP1A2 (0.45) | MTNR1AMTNR1BL3MBTL1MAPTTDP1 | |
| SCHEMBL14884628 | 0.75 | HASPIN (0.55) | HPGDL3MBTL1MAPTTDP1LMNA | |
| SCHEMBL10688770 | 0.75 | CYP1A2 (0.42) | MTNR1APPARGCYP1A2CYP2A6CLK1 | |
| SCHEMBL10694029 | 0.73 | HTR2A (0.49) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |