Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540107 | 0.89 | MMP12 (0.46) | MMP12MMP13SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL46638 | 0.84 | HSD17B10 (0.61) | MMP12MMP13HSD17B10SMN1; SMN2SLC6A3 | |
| SCHEMBL8588995 | 0.82 | SLC6A4 (0.39) | MMP12MMP13SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL1455083 | 0.79 | PLAAT3 (0.50) | HSD17B10SMN1; SMN2SLC6A3HDAC3MAPK1 | |
| SCHEMBL28228920 | 0.78 | MMP12 (0.49) | MMP12MMP13HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL712396 | 0.77 | MAPT (0.62) | MMP12MMP13HSD17B10SMN1; SMN2SLC6A3 | |
| SCHEMBL2407621 | 0.77 | SMN1; SMN2 (0.46) | MMP12MMP13HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL11572521 | 0.77 | HDAC3 (0.58) | SMN1; SMN2MEN1KMT2ASLC6A3HDAC3 | |
| SCHEMBL38664087 | 0.76 | SMN1; SMN2 (0.52) | MMP12MMP13HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL3866365 | 0.76 | PLAAT3 (0.50) | HSD17B10SMN1; SMN2KMT2ASLC6A3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |