Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695915 | 0.89 | MMP12 (0.44) | MMP12MMP13SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL9135914 | 0.83 | FFAR1 (0.50) | MMP12KDM4EMEN1KMT2AATM | |
| SCHEMBL7953221 | 0.82 | ALDH1A1 (0.59) | MMP12MMP13SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL46690 | 0.82 | FFAR1 (0.59) | MMP12MMP13FFAR1FFAR4 | |
| SCHEMBL5677026 | 0.81 | ALDH1A1 (0.49) | MMP12MMP13SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2407621 | 0.80 | SMN1; SMN2 (0.46) | MMP12MMP13SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13485787 | 0.78 | HDAC1 (0.61) | SLC6A4 | |
| SCHEMBL835726 | 0.78 | CYP4F2 (0.47) | MMP12MMP13KDM4EKMT2AFFAR1 | |
| SCHEMBL4979314 | 0.78 | PLAAT3 (0.45) | MEN1KMT2AFFAR1PLAAT3PLAAT5 | |
| SCHEMBL30799017 | 0.78 | ALDH1A1 (0.48) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841425-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-23 | — | — | EP | disclosed |
| US-9133167-B2 | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2015-09-15 | — | — | US | disclosed |
| US-20150065502-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN-CILAG (FR) | 2015-03-05 | — | — | US | disclosed |
| EP-2841425-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | Janssen Pharmaceutica, N.V. (BE) | 2015-03-04 | — | — | EP | disclosed |
| WO-2013160435-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2013-10-31 | — | — | WO | disclosed |
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065502-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | NQO2, NDUFB5, NDUFB7 | MMP12 2125/4885MMP13 4310/4885SMN1; SMN2 2488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.