Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312177 | 0.94 | IGF1R (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL19612740 | 0.92 | NAAA (0.51) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL1446802 | 0.88 | FFAR1 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL11390257 | 0.83 | TDP1 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL661277 | 0.82 | PLAAT3 (0.51) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL11572521 | 0.82 | HDAC3 (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL764952 | 0.82 | SMN1; SMN2 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL105767 | 0.82 | HSD17B10 (0.52) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL25172929 | 0.80 | HSD17B10 (0.65) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL4375147 | 0.80 | TDP1 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2647635-B1 | PYRROLE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | DAIICHI SANKYO CO LTD (JP) | 2015-08-19 | — | — | EP | disclosed |
| EP-2647635-B1 | PYRROLE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | DAIICHI SANKYO CO LTD (JP) | 2015-08-19 | — | — | EP | disclosed |
| US-8846943-B2 | Pyrrole derivative and process for production thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-09-30 | — | — | US | disclosed |
| US-8846943-B2 | Pyrrole derivative and process for production thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-09-30 | — | — | US | disclosed |
| US-8846943-B2 | Pyrrole derivative and process for production thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-09-30 | — | — | US | disclosed |
| US-20140039198-A1 | PYRROLE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20140039198-A1 | PYRROLE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20140039198-A1 | PYRROLE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-02-06 | — | — | US | disclosed |
| EP-2647635-A1 | PYRROLE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-09 | — | — | EP | disclosed |
| EP-2647635-A1 | PYRROLE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-09 | — | — | EP | disclosed |
| US-7910617-B2 | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound | SANKYO COMPANY, LIMITED (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20070191468-A1 | Amino alcohol compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1733724-A1 | AMINO ALCOHOL COMPOUND | Sankyo Company, Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039198-A1 | PYRROLE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | FKBP5, FKBP4, PDCD5 | PLAAT3 2517/4885PLAAT5 1787/4885PLAAT2 3489/4885 |
| US-20070191468-A1 | Amino alcohol compound | ADH1A, ADH1C, BCAT1 | PLAAT3 2204/4885PLAAT5 2753/4885PLAAT2 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.