Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695963 | 0.89 | ALDH1A1 (0.41) | MAPTKMT2ACA12CA9CA1 | |
| SCHEMBL10697122 | 0.88 | MAPT (0.34) | MAPTRARARARBRARGALDH1A1 | |
| SCHEMBL10696935 | 0.87 | MAPT (0.34) | MAPTSMN1; SMN2RARARARBRARG | |
| SCHEMBL10697007 | 0.86 | RARA (0.38) | MAPTSMN1; SMN2RARARARBRARG | |
| SCHEMBL7268034 | 0.86 | ALOX5 (0.40) | MAPTRAB9AMEN1KMT2APOLB | |
| SCHEMBL9377257 | 0.80 | RAB9A (0.39) | MAPTRAB9AMEN1KMT2APOLB | |
| SCHEMBL8084285 | 0.80 | RAB9A (0.39) | MAPTRAB9AMEN1KMT2APOLB | |
| SCHEMBL10697804 | 0.79 | MAPT (0.34) | MAPTALDH1A1KDM4E | |
| SCHEMBL7269375 | 0.79 | PDE4A (0.42) | MAPTCASP3LMNAKDM4E | |
| SCHEMBL9733491 | 0.79 | CASP3 (0.36) | MAPTRAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |