Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696935 | 0.90 | MAPT (0.34) | MAPTRARARARBRARGKDM4E | |
| SCHEMBL10695615 | 0.88 | MAPT (0.40) | MAPTRARARARBRARGKDM4E | |
| SCHEMBL10697007 | 0.87 | RARA (0.38) | MAPTRARARARBRARGKDM4E | |
| SCHEMBL10695963 | 0.85 | ALDH1A1 (0.41) | MAPTRARARARBALDH1A1 | |
| SCHEMBL7277136 | 0.85 | S100A4 (0.38) | RARARARBRARGKDM4EALDH1A1 | |
| SCHEMBL10697804 | 0.82 | MAPT (0.34) | MAPTKDM4EALDH1A1 | |
| SCHEMBL7269375 | 0.82 | PDE4A (0.42) | MAPTKDM4E | |
| SCHEMBL10695563 | 0.81 | CA9 (0.36) | MAPTALDH1A1S100A4 | |
| SCHEMBL8077225 | 0.79 | HSD17B1 (0.35) | MAPTHSD17B1KDM4EALDH1A1S100A4 | |
| SCHEMBL7293261 | 0.78 | CCNC (0.33) | MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |