Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533212 | 0.86 | PARP1 (0.40) | ELANEPARP1MAPTPOLBRXFP1 | |
| SCHEMBL9770716 | 0.83 | PARP1 (0.44) | ELANEPARP1MAPTPOLBRXFP1 | |
| SCHEMBL10695218 | 0.83 | ELANE (0.40) | ELANEPARP1MAPTPIK3CDPIK3CG | |
| SCHEMBL10696348 | 0.80 | PDE10A (0.43) | ELANEPARP1MAPTPOLBRXFP1 | |
| SCHEMBL10696794 | 0.77 | KDM4E (0.49) | MAPTPOLBRXFP1KDM4EMEN1 | |
| SCHEMBL9534833 | 0.74 | CYP1A2 (0.50) | ELANEPARP1MAPTMEN1ALDH1A1 | |
| SCHEMBL10696516 | 0.73 | PARP1 (0.43) | ELANEPARP1MAPTPOLBRXFP1 | |
| SCHEMBL9536653 | 0.72 | ELANE (0.40) | ELANEPARP1MAPTPIK3CDPIK3CG | |
| SCHEMBL9533229 | 0.71 | PARP1 (0.40) | ELANEPARP1MAPTPOLBRXFP1 | |
| SCHEMBL9535817 | 0.69 | PARP1 (0.44) | ELANEPARP1MAPTPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |