Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091196 | 0.81 | MAOA (0.47) | MAOAMAOBMMP2MMP3MMP9 | |
| SCHEMBL15730582 | 0.81 | MAOA (0.51) | MAOAMAOBPGR | |
| SCHEMBL11514976 | 0.77 | PGR (0.47) | MAOAMAOBPGRMAPTTDP1 | |
| SCHEMBL9195493 | 0.75 | PARP1 (0.59) | MAOAMAOBMAPTTDP1L3MBTL1 | |
| SCHEMBL8202277 | 0.73 | PGR (0.49) | MAOAMAOBPGRMAPTL3MBTL1 | |
| SCHEMBL30088920 | 0.73 | BRPF1 (0.53) | PGRMAPTTDP1L3MBTL1 | |
| SCHEMBL260994 | 0.73 | BRPF1 (0.53) | PGRMAPTTDP1L3MBTL1 | |
| SCHEMBL19054962 | 0.73 | BRPF1 (0.53) | PGRMAPTTDP1L3MBTL1 | |
| SCHEMBL24112730 | 0.72 | PGR (0.54) | PGRHPGD | |
| SCHEMBL9651557 | 0.72 | PGR (0.54) | PGRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255178-A2 | Process for preparing hetero aryl and aryl alkanoic acids | Nobel Chemicals AB (SE) | 1988-02-03 | — | — | EP | disclosed |