Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249330 | 0.91 | ALPG (0.55) | ALPGATAD2NPC1RAB9APOLB | |
| SCHEMBL10696742 | 0.84 | MMP13 (0.38) | ALPGNPC1RAB9AAKR1B1MAPT | |
| SCHEMBL9770670 | 0.81 | ALPG (0.55) | ALPGNPC1RAB9ADYRK1ASMN1; SMN2 | |
| SCHEMBL11014615 | 0.81 | ALPG (0.60) | ALPGRAB9APOLBKDM4EHSD17B10 | |
| SCHEMBL11397996 | 0.74 | AKR1B1 (0.37) | ALPGNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11391279 | 0.72 | ALPG (0.35) | ALPG | |
| SCHEMBL28345154 | 0.72 | ALPG (0.54) | ALPGNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL11208277 | 0.71 | ALPG (0.74) | ALPGSMN1; SMN2CYP1A2POLBKDM4E | |
| SCHEMBL10696374 | 0.71 | KDM4E (0.49) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11263888 | 0.70 | ALPG (0.82) | ALPGSMN1; SMN2CYP1A2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |