Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014615 | 0.93 | ALPG (0.60) | ALPGPLA2G2AALDH1A1KDM4EHPGD | |
| SCHEMBL9770699 | 0.84 | ALDH1A1 (0.39) | ALPGALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28345238 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL10696645 | 0.81 | ALPG (0.53) | ALPGPLA2G2AALDH1A1KDM4EHPGD | |
| SCHEMBL11249330 | 0.81 | ALPG (0.55) | ALPGPLA2G2AALDH1A1KDM4EHPGD | |
| SCHEMBL11263888 | 0.76 | ALPG (0.82) | ALPGPLA2G2AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL11263169 | 0.75 | ALPG (0.80) | ALPGPLA2G2AALDH1A1KDM4EHPGD | |
| SCHEMBL18548584 | 0.75 | SMN1; SMN2 (0.48) | ALPGALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29660149 | 0.75 | SMN1; SMN2 (0.48) | ALPGALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28345154 | 0.74 | ALPG (0.54) | ALPGALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0006114-B1 | 7-METHOXY-5-OXO-5H-THIAZOLO(2,3-B)QUINAZOLIN-2-CARBOXYLIC ACID AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-04-07 | — | — | EP | disclosed |
| EP-0006114-A1 | 7-Methoxy-5-oxo-5H-thiazolo(2,3-b)quinazolin-2-carboxylic acid and its pharmaceutically acceptable salts, process for their preparation and medicines containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-01-09 | — | — | EP | disclosed |
| US-4168380-A | ANTIALLERGEN | HOFFMANN-LA ROCHE INC. (US) | 1979-09-18 | — | — | US | disclosed |