Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397996 | 0.90 | AKR1B1 (0.37) | MMP13AKR1B1ALPGDHODHRXFP1 | |
| SCHEMBL10696645 | 0.84 | ALPG (0.53) | AKR1B1ALPGLMNAMAPTNPC1 | |
| SCHEMBL9770699 | 0.82 | ALDH1A1 (0.39) | MMP13AKR1B1ALPGDHODHRXFP1 | |
| SCHEMBL11014908 | 0.79 | DHODH (0.40) | MMP13AKR1B1ALPGDHODHTYMS | |
| SCHEMBL11391279 | 0.70 | ALPG (0.35) | ALPG | |
| SCHEMBL11270745 | 0.68 | ALPG (0.67) | AKR1B1ALPGDHODHRXFP1LMNA | |
| SCHEMBL11269248 | 0.67 | ALPG (0.48) | ALPG | |
| SCHEMBL9770670 | 0.66 | ALPG (0.55) | ALPGLMNAMAPTNPC1RAB9A | |
| SCHEMBL11014615 | 0.65 | ALPG (0.60) | ALPGDHODHLMNAMAPTKMT2A | |
| SCHEMBL11279272 | 0.65 | ALPG (0.45) | AKR1B1ALPGLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |