Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SDHB | P21912 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363011 | 0.79 | KDM4E (0.41) | KMT2AALDH1A1LMNAHTTSDHB | |
| SCHEMBL10364788 | 0.74 | KDM4E (0.38) | ALDH1A1LMNAHTTPTGS2SDHB | |
| SCHEMBL10694814 | 0.72 | MAPT (0.44) | KMT2AALDH1A1GAALMNAHTT | |
| SCHEMBL6734856 | 0.72 | CYP3A4 (0.44) | ALDH1A1GAALMNAHTTGFER | |
| SCHEMBL10364438 | 0.72 | MAPT (0.40) | ALDH1A1GAALMNAHTTSDHB | |
| SCHEMBL10696730 | 0.71 | KDM4E (0.48) | KMT2AALDH1A1LMNAHTTSDHB | |
| SCHEMBL6730092 | 0.71 | LMNA (0.44) | ALDH1A1LMNAKDM4EPOLBHPGD | |
| SCHEMBL10333985 | 0.71 | KDM4E (0.40) | CYP1A2KMT2AALDH1A1GAALMNA | |
| SCHEMBL6730105 | 0.70 | KDM4E (0.43) | KMT2AALDH1A1LMNAHTTSDHB | |
| SCHEMBL11904550 | 0.70 | MEN1 (0.47) | CYP1A2KMT2AGAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276204-A2 | Pyridine gametocides | Monsanto Company (US) | 1988-07-27 | — | — | EP | claimed |