Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032782 | 0.77 | TSHR (0.48) | ALOX5ALDH1A1PTGS2SIGMAR1KMT2A | |
| SCHEMBL196307 | 0.64 | NOTUM (0.52) | NOTUMALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL25198803 | 0.63 | ALDH1A1 (0.42) | ALOX5ALDH1A1LMNAKDM4ESIGMAR1 | |
| Chlorophthalium SCHEMBL315018 | 0.63 | MEN1 (0.55) | ALOX5ALDH1A1LMNAKMT2AMEN1 | |
| Chlorobenzene SCHEMBL4439009 | 0.62 | TSHR (0.68) | ALDH1A1LMNAKDM4ESIGMAR1KMT2A | |
| SCHEMBL5496769 | 0.62 | HTR2A (0.64) | ALDH1A1TSHR | |
| SCHEMBL29724224 | 0.62 | HTR2A (0.64) | ALDH1A1TSHR | |
| SCHEMBL24103508 | 0.62 | SIGMAR1 (0.64) | ALDH1A1LMNAKDM4ESIGMAR1HTR3E | |
| SCHEMBL1822749 | 0.62 | HTR3E (0.64) | ALDH1A1LMNAKDM4ESIGMAR1HTR3E | |
| SCHEMBL2725729 | 0.61 | MAPT (0.59) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260724-A2 | Intermediates for the production of 2-substituted phenyl-4,5,6,7-tetrahydro-2H-isoindole-1,3-diones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-23 | — | — | EP | disclosed |