SCHEMBL10697268

SCHEMBL10697268

C=C(Br)c1ccccc1.C=Cc1cccc(Cl)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
PPP1R15A O75807 1/20 0.37
MELK Q14680 1/20 0.37
PPP1R15B Q5SWA1 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 2/20 0.37
KMT2A Q03164 2/20 0.37
GSR P00390 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PTGS2 P35354 1/20 0.34
TSHR P16473 2/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
MAPT P10636 1/20 0.33
EGFR P00533 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974727 0.84 ALDH1A1 (0.48) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL30587141 0.80 ALDH1A1 (0.65) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL40188 0.80 ALDH1A1 (0.65) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL5491734 0.79 ALDH1A1 (0.78) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
Acrylic Acid SCHEMBL28294924 0.76 ALDH1A1 (0.50) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
Maleic Acid SCHEMBL28081511 0.75 ALDH1A1 (0.48) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL10438866 0.73 ALDH1A1 (0.56) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL9985258 0.73 ALDH1A1 (0.55) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL297455 0.72
SCHEMBL5047647 0.71 ALDH1A1 (0.64) ALDH1A1NPSR1LMNAKMT2AGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0272412-A2 Aromatic carbonate articles bonded by a photocured acrylic composition GENERAL ELECTRIC COMPANY (US) 1988-06-29 EP disclosed