SCHEMBL10697594

SCHEMBL10697594

OCCONc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
RECQL P46063 2/20 0.46
KCNH3 Q9ULD8 2/20 0.40
IDO1 P14902 1/20 0.39
GAA P10253 2/20 0.36
MAPT P10636 2/20 0.36
MCL1 Q07820 1/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 3/20 0.36
HSD17B10 Q99714 2/20 0.36
CTSD P07339 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 1/20 0.35
MAPK1 P28482 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27584589 0.84 KCNH3 (0.42) ALDH1A1RECQLKCNH3GAAMAPT
SCHEMBL11119765 0.82 ALDH1A1 (0.39) ALDH1A1RECQLKCNH3IDO1MAPT
SCHEMBL25333055 0.81 ALDH1A1 (0.42) ALDH1A1RECQLIDO1MAPTHPGD
SCHEMBL11313866 0.81 IDO1 (0.42) ALDH1A1RECQLIDO1GAAMAPT
SCHEMBL6131910 0.80 CA2 (0.38) ALDH1A1RECQLIDO1GAAMAPT
SCHEMBL2911694 0.79 HDAC1 (0.42) ALDH1A1IDO1MAPTTDP1HSD17B10
SCHEMBL3366323 0.79 HDAC1 (0.42) ALDH1A1IDO1MAPTTDP1HSD17B10
SCHEMBL28630486 0.78 MAPT (0.41) ALDH1A1GAAMAPTHPGDTDP1
SCHEMBL1401823 0.78 APP (0.46) ALDH1A1RECQLHPGDHSD17B10CYP3A4
SCHEMBL33691 0.78 MAPT (0.39) ALDH1A1GAAMAPTHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117797305-A Meningeal sealing gel and preparation method and application thereof 上海瑞凝生物科技有限公司 2024-04-02 CN claimed
CN-100432052-C Synthetic method for methoxy indole UNIV TIANJIN (CN) 2008-11-12 CN claimed
CN-1944405-A Synthetic method for methoxy indole UNIV TIANJIN (CN) 2007-04-11 CN claimed
CN-117797305-A Meningeal sealing gel and preparation method and application thereof 上海瑞凝生物科技有限公司 2024-04-02 CN disclosed
CN-107954916-A A kind of 5- methoxy-Indole production methods of the Woelm Alumina composite catalyst based on absorption tetrafluoroacetate 苏州盖德精细材料有限公司 2018-04-24 CN disclosed
CN-100432052-C Synthetic method for methoxy indole UNIV TIANJIN (CN) 2008-11-12 CN disclosed
CN-1944405-A Synthetic method for methoxy indole UNIV TIANJIN (CN) 2007-04-11 CN disclosed
EP-0273368-A2 Process for producing thermoset resin TEIJIN LIMITED (JP) 1988-07-06 EP disclosed