Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979097 | 0.81 | CYP3A4 (0.37) | MAPTRAB9AAPPALDH1A1CYP3A4 | |
| SCHEMBL6131910 | 0.81 | CA2 (0.38) | MAPTRAB9AAPPALDH1A1CYP3A4 | |
| SCHEMBL28630486 | 0.79 | MAPT (0.41) | MAPTRAB9AALDH1A1L3MBTL1HTT | |
| SCHEMBL1401823 | 0.79 | APP (0.46) | APPALDH1A1CYP3A4TP53THRB | |
| SCHEMBL10697594 | 0.78 | ALDH1A1 (0.46) | MAPTRAB9AALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL6229318 | 0.77 | DDX3X (0.46) | MAPTRAB9AALDH1A1CYP3A4MEN1 | |
| SCHEMBL27763969 | 0.76 | TSHR (0.46) | MAPTRAB9AALDH1A1CYP3A4L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28429247 | 0.76 | DDX3X (0.44) | MAPTALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL5718659 | 0.75 | NR4A1 (0.36) | MAPTRAB9AALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL2026345 | 0.74 | TDP1 (0.46) | MAPTRAB9AALDH1A1CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1769 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | L'OREAL (FR) | 2023-01-17 | — | — | US | claimed |
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2020-12-17 | — | — | US | claimed |
| EP-3638200-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING AT LEAST ONE BLUE, PURPLE OR GREEN DYE AND AT LEAST ONE DISULFIDE, THIOL OR PROTECTED THIOL FLUORESCENT DYE | L'Oreal (FR) | 2020-04-22 | — | — | EP | claimed |
| EP-3464247-B1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | OREAL (FR) | 2020-03-11 | — | — | EP | claimed |
| EP-3464247-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'Oréal (FR) | 2019-04-10 | — | — | EP | claimed |
| WO-2017202884-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2017-11-30 | — | — | WO | claimed |
| EP-0850636-B2 | Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition | OREAL (FR) | 2013-11-20 | — | — | EP | claimed |
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | claimed |
| EP-0850637-B2 | Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition | OREAL (FR) | 2010-11-10 | — | — | EP | claimed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | claimed |
| US-5814106-A | HAIR COLORING DYES; NONTOXIC, DISCOLORATION INHIBITION, WEATHERPROOFING, STABILITY, UNIFORM COLOR INTENSITY | L'OREAL (FR) | 1998-09-29 | — | — | US | claimed |
| US-5769903-A | Composition for the oxidation dyeing of keratin fibers, comprising an oxidation base, an indole coupler and an additional heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-06-23 | — | — | US | claimed |
| US-5752983-A | Composition for oxidation dyeing of keratinous fibres comprising an oxidation base, a coupler, and 4-hydroxyindole as coupler and dyeing process with this composition | L'OREAL (FR) | 1998-05-19 | — | — | US | claimed |
| US-5735909-A | Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler | L'OREAL (FR) | 1998-04-07 | — | — | US | claimed |
| EP-0766958-B1 | Oxidation dyeing composition for keratinous fibers comprising 2-amino-3-hydroxypyridine and an oxidation base and dyeing process | OREAL (FR) | 1997-11-19 | — | — | EP | claimed |
| US-5620484-A | READY TO APPLY COMPOSITION FOR DYEING HAIR HAVING PH LESS THAN 7 | L'OREAL (FR) | 1997-04-15 | — | — | US | claimed |
| EP-0733356-B1 | Composition for dyeing keratinous fibres and dyeing process using the said composition | OREAL (FR) | 1997-03-26 | — | — | EP | claimed |
| EP-0728465-B1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| EP-0722712-B1 | Keratinous fiber oxidation dyeing composition and the dyeing process using this composition | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| EP-0684035-B1 | Keratineous fibres oxidation dyeing composition containing a derivative of paraphenylenediamine and a 6-hydroxy 1,4-benzoxazine | OREAL (FR) | 1996-09-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | KRT18, ALK, AOC1 | MAPT 148/4885RAB9A 4051/4885APP 1313/4885 |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | KRT18, KRTCAP2, FASN | MAPT 687/4885RAB9A 3629/4885APP 2040/4885 |
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | KRT18, ALK, AOC1 | MAPT 169/4885RAB9A 4177/4885APP 1242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.