Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696448 | 0.94 | KEAP1 (0.44) | L3MBTL1SMN1; SMN2CHRM3KEAP1NFE2L2 | |
| SCHEMBL10697581 | 0.92 | KEAP1 (0.43) | L3MBTL1SMN1; SMN2CHRM3LMNAKEAP1 | |
| SCHEMBL6924068 | 0.79 | KEAP1 (0.51) | L3MBTL1SMN1; SMN2CHRM3LMNANAPRT | |
| SCHEMBL17490358 | 0.76 | SMN1; SMN2 (0.53) | L3MBTL1SMN1; SMN2CHRM3RIPK1BLM | |
| SCHEMBL8972314 | 0.76 | SMN1; SMN2 (0.44) | L3MBTL1SMN1; SMN2CHRM3RIPK1BLM | |
| SCHEMBL5074249 | 0.75 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2BLMCYP2D6LMNA | |
| SCHEMBL505194 | 0.75 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2BLMCYP2D6LMNA | |
| SCHEMBL4243455 | 0.75 | KEAP1 (0.50) | CHRM3GLAKEAP1NFE2L2 | |
| SCHEMBL4243228 | 0.75 | KEAP1 (0.50) | CHRM3GLAKEAP1NFE2L2 | |
| SCHEMBL27749385 | 0.75 | KEAP1 (0.50) | CHRM3GLAKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253681-A2 | Cycloalkyl-substituted 4-pyridyl derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-01-20 | — | — | EP | disclosed |