Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628237 | 0.70 | GID4 (0.33) | GID4IGF1RALOX15DDB1CRBN | |
| SCHEMBL1345184 | 0.66 | HTR2A (0.32) | — | |
| SCHEMBL31290248 | 0.65 | ALDH1A1 (0.41) | — | |
| SCHEMBL28642348 | 0.64 | ACHE (0.32) | — | |
| SCHEMBL1403725 | 0.64 | POLL (0.36) | — | |
| SCHEMBL10920557 | 0.64 | CYP3A4 (0.36) | — | |
| SCHEMBL812885 | 0.63 | HPGD (0.31) | — | |
| SCHEMBL24682 | 0.63 | — | — | |
| SCHEMBL10695089 | 0.62 | TSHR (0.41) | — | |
| Ammonia Solution, Strong SCHEMBL6216585 | 0.62 | IGF1R (0.50) | GID4IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279707-A2 | Aryloxymethyl derivatives of nitrogenous heterocyclic methanols and ethers thereof having cardiovascular activity | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-24 | — | — | EP | disclosed |