SCHEMBL9628237

SCHEMBL9628237

[c]1ccc2c(c1)CCC2c1ccc2c(c1)CCCC2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GID4 Q8IVV7 1/20 0.33
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31
IGF1R P08069 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765982 0.76 PDGFRA (0.45) DDB1CRBNIGF1RALOX15
SCHEMBL7986478 0.75 FABP4 (0.33)
SCHEMBL17079721 0.74 IGF1R (0.53) GID4IGF1RALOX15
SCHEMBL16105106 0.72 SLC6A2 (0.41) DDB1CRBN
SCHEMBL10920557 0.70 CYP3A4 (0.36)
SCHEMBL10697922 0.70 GID4 (0.35) GID4DDB1CRBNIGF1RALOX15
SCHEMBL4812053 0.67 CHRNB2 (0.30)
SCHEMBL22225 0.67 TSHR (0.46)
SCHEMBL548000 0.67 GID4 (0.37) GID4
SCHEMBL5688182 0.67 HTR2A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4107065-A P-ACYLAMINOBENZENESULFONYL CHLORIDE OR BROMIDE COLGATE-PALMOLIVE COMPANY (US) 1978-08-15 US claimed
EP-0233834-B1 INSECTICIDAL TRIFLUORMETHYL ALKANE DERIVATIVES SCHERING AKTIENGESELLSCHAFT (DE) 1992-04-22 EP disclosed