SCHEMBL10698086

SCHEMBL10698086

Cc1cc(-c2ccccc2)cc(C(=O)O)c1OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.56
PPARG P37231 1/20 0.56
PPARA Q07869 1/20 0.56
DHODH Q02127 4/20 0.53
MRGPRX4 Q96LA9 1/20 0.51
PTGER1 P34995 1/20 0.48
PTPN1 P18031 3/20 0.47
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
BAK1 Q16611 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9191607 0.84 DHODH (0.49) MCL1DHODHMRGPRX4PTGER1PTPN1
SCHEMBL27678664 0.84 PTGER1 (0.51) MCL1MRGPRX4PTGER1PTPN1LMNA
SCHEMBL4551575 0.82 DHODH (0.46) MCL1DHODHPTGER1PTPN1BAK1
SCHEMBL7916872 0.82 MAOB (0.52) MCL1MRGPRX4PTGER1PTPN1LMNA
SCHEMBL4132651 0.81 MCL1 (0.61) MCL1DHODHMRGPRX4PTGER1
SCHEMBL12379065 0.79 PTGER1 (0.53) MCL1MRGPRX4PTGER1PTPN1LMNA
SCHEMBL1396290 0.79 ALDH1A1 (0.57) MCL1PTGER1PTPN1HPGD
SCHEMBL9191728 0.79 CNR1 (0.59) MCL1PPARGPPARADHODHPTPN1
SCHEMBL4133504 0.78 MCL1 (0.58) MCL1PPARGPPARADHODHMRGPRX4
Hydrochloric Acid SCHEMBL18037169 0.78 ALDH1A1 (0.55) MCL1PTGER1PTPN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed