Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.58 |
| ▸ | GLRA1 | P23415 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.44 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146025 | 0.90 | MCL1 (0.49) | MCL1GLRA1MRGPRX4PDE4APDE4B | |
| SCHEMBL4132651 | 0.84 | MCL1 (0.61) | MCL1MRGPRX4PDE4APDE4BPDE4C | |
| SCHEMBL4819103 | 0.78 | MAOB (0.59) | MCL1GLRA1MRGPRX4 | |
| SCHEMBL10698086 | 0.78 | MCL1 (0.56) | MCL1MRGPRX4PPARGPPARADHODH | |
| Lithium Ion SCHEMBL29695998 | 0.76 | MAOB (0.57) | MCL1GLRA1MRGPRX4 | |
| SCHEMBL128058 | 0.74 | GLRA1 (0.57) | GLRA1MRGPRX4PTGER1 | |
| SCHEMBL27678664 | 0.74 | PTGER1 (0.51) | MCL1GLRA1MRGPRX4PTGER1 | |
| SCHEMBL4566984 | 0.74 | MCL1 (0.54) | MCL1GLRA1MRGPRX4PTGER1 | |
| SCHEMBL12941391 | 0.74 | RXRA (0.51) | MCL1GLRA1MRGPRX4PTGER1 | |
| SCHEMBL4671597 | 0.73 | ADRB3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1932826-A1 | METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
| EP-1932826-A1 | METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | ALDH7A1, DDC, ADH5 | MCL1 3289/4885GLRA1 4248/4885MRGPRX4 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.