Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698322 | 0.94 | ALDH1A1 (0.37) | TSHRCES2HCAR2 | |
| SCHEMBL10698192 | 0.89 | TSHR (0.45) | TSHRCES2NAAALMNAEPHX1 | |
| SCHEMBL10698317 | 0.82 | ALDH1A1 (0.38) | TSHRCES2LMNAPLA2G2C | |
| SCHEMBL10456591 | 0.75 | HCAR2 (0.38) | TSHRCES2NAAAHCAR2LMNA | |
| SCHEMBL30595889 | 0.72 | LMNA (0.37) | TSHRCES2NAAAHCAR2LMNA | |
| SCHEMBL10699703 | 0.72 | TSHR (0.51) | TSHRCES2NAAAHCAR2LMNA | |
| SCHEMBL11224059 | 0.71 | SMPD1 (0.42) | — | |
| SCHEMBL9852414 | 0.71 | HCAR2 (0.46) | TSHRCES2NAAAHCAR2EPHX1 | |
| SCHEMBL28586771 | 0.70 | GPR84 (0.44) | TSHRLMNA | |
| SCHEMBL15914715 | 0.70 | PLA2G2C (0.35) | CES2NAAAHCAR2LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289933-A2 | Graft polymerization precurser and method manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0277608-A2 | Graft polymerization preformer and method of manufacturing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-08-10 | — | — | EP | disclosed |