Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 13/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698275 | 1.00 | P4HB (0.51) | P4HBPDCD1CD274CYP4F2CYP4A11 | |
| SCHEMBL9514413 | 0.88 | PDCD1 (0.57) | P4HBPDCD1CD274FBP1MAOA | |
| SCHEMBL9514417 | 0.88 | PDCD1 (0.57) | P4HBPDCD1CD274FBP1MAOA | |
| SCHEMBL9201387 | 0.80 | P4HB (0.47) | P4HBPDCD1CD274CYP4F2CYP4A11 | |
| SCHEMBL9201390 | 0.80 | P4HB (0.47) | P4HBPDCD1CD274CYP4F2CYP4A11 | |
| SCHEMBL6947907 | 0.80 | P4HB (0.58) | P4HBPDCD1CD274MAOAMAOB | |
| SCHEMBL21901276 | 0.80 | SLC6A19 (0.51) | CYP4F2CYP4A11MAOAMAOBAKT1 | |
| SCHEMBL9101368 | 0.78 | TBXAS1 (0.49) | P4HBPDCD1CD274FBP1MAOA | |
| SCHEMBL7571411 | 0.78 | AKT1 (0.62) | CYP4F2CYP4A11MAOBAKT1HDAC4 | |
| SCHEMBL19452350 | 0.78 | AKT1 (0.62) | CYP4F2CYP4A11MAOBAKT1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271287-A2 | Quinoline dioic acids and amides | MERCK FROSST CANADA INC. (CA) | 1988-06-15 | — | — | EP | disclosed |