Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699541 | 0.85 | HSD11B1 (0.53) | HSD11B1ALDH1A1LMNAHTR2A | |
| SCHEMBL10698593 | 0.81 | LMNA (0.47) | HSD11B1NPC1ALDH1A1LMNAHTT | |
| SCHEMBL9374411 | 0.77 | ALDH1A1 (0.49) | HSD11B1ALDH1A1LMNAHTT | |
| SCHEMBL5756941 | 0.77 | GAA (0.46) | HSD11B1ALDH1A1GAALMNA | |
| SCHEMBL7300582 | 0.76 | LMNA (0.51) | GAALMNAHTR2A | |
| SCHEMBL6009365 | 0.73 | HTR2A (0.46) | GAALMNAHTR2A | |
| SCHEMBL5756938 | 0.71 | HTR2A (0.52) | HTR2A | |
| SCHEMBL5757096 | 0.69 | ALDH1A1 (0.46) | NPC1ALDH1A1MGLLMAPTHTT | |
| SCHEMBL10699537 | 0.67 | HSD11B1 (0.53) | HSD11B1ALDH1A1LMNAHTTHTR2A | |
| SCHEMBL7868805 | 0.67 | KYNU (0.62) | ALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294183-A1 | Use of ethylamine derivatives as antihypertensive agents | AJINOMOTO CO., INC. (JP) | 1988-12-07 | — | — | EP | disclosed |