SCHEMBL10698637

SCHEMBL10698637

CCCCN1CC=C(c2csc(N)n2)CC1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.40
SIGMAR1 Q99720 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10697120 0.92 KDM4E (0.42)
Hydrochloric Acid SCHEMBL10699302 0.91 KDM4E (0.44)
SCHEMBL9451944 0.79
SCHEMBL10697680 0.79 DRD2 (0.48) SIGMAR1
SCHEMBL10698234 0.77 MAPT (0.44)
SCHEMBL9728463 0.76 HTR6 (0.43) HTR6SIGMAR1
SCHEMBL10697938 0.75 TYR (0.41)
SCHEMBL9833493 0.74
SCHEMBL9833971 0.74
SCHEMBL9728514 0.73 HTR6 (0.36) HTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0280873-A1 Piperidines, medicines containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1988-09-07 EP disclosed