Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697120 | 0.81 | KDM4E (0.42) | ALDH1A1MAPTKMT2A | |
| SCHEMBL9451990 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTALOX15KMT2ATAAR1 | |
| Hydrochloric Acid SCHEMBL10699302 | 0.80 | KDM4E (0.44) | ALDH1A1MAPTKMT2A | |
| SCHEMBL10698637 | 0.79 | HTR6 (0.40) | SIGMAR1 | |
| SCHEMBL30484775 | 0.77 | SIGMAR1 (0.66) | DRD2DRD4DRD3SIGMAR1MAOA | |
| Water SCHEMBL10698996 | 0.77 | ALDH1A1 (0.40) | DRD2DRD4DRD3ALDH1A1ALOX15 | |
| SCHEMBL10332834 | 0.76 | SIGMAR1 (0.53) | DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL10698234 | 0.74 | MAPT (0.44) | DRD2DRD4DRD3ALDH1A1MAPT | |
| SCHEMBL8583003 | 0.71 | SIGMAR1 (0.52) | DRD2DRD4DRD3MAPTSIGMAR1 | |
| SCHEMBL6437677 | 0.71 | SIGMAR1 (0.52) | DRD2DRD4DRD3SIGMAR1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |