Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728463 | 0.82 | HTR6 (0.43) | HTR6SIGMAR1 | |
| SCHEMBL9728560 | 0.82 | — | — | |
| SCHEMBL10698637 | 0.73 | HTR6 (0.40) | HTR6SIGMAR1 | |
| SCHEMBL9729054 | 0.71 | RAD52 (0.40) | — | |
| SCHEMBL10698534 | 0.69 | HTR6 (0.39) | HTR6DRD2SIGMAR1 | |
| SCHEMBL10697120 | 0.65 | KDM4E (0.42) | — | |
| Hydrochloric Acid SCHEMBL9870487 | 0.65 | SIGMAR1 (0.57) | DRD2DRD3SIGMAR1 | |
| SCHEMBL7270081 | 0.65 | SIGMAR1 (0.51) | DRD2DRD3SIGMAR1 | |
| SCHEMBL14601668 | 0.65 | SIGMAR1 (0.60) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10699302 | 0.64 | KDM4E (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128340-A | Thiazole derivatives | AKZO N.V. (NL) | 1992-07-07 | — | — | US | disclosed |
| EP-0368384-A1 | Thiazole derivatives | AKZO N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |