Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10699302 | 0.99 | KDM4E (0.44) | KDM4EMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL10698637 | 0.92 | HTR6 (0.40) | — | |
| SCHEMBL10697680 | 0.81 | DRD2 (0.48) | ALDH1A1MAPTKMT2A | |
| SCHEMBL10698234 | 0.80 | MAPT (0.44) | KDM4EALDH1A1MAPT | |
| SCHEMBL10698628 | 0.78 | ABL1 (0.45) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9451955 | 0.78 | CHRM2 (0.46) | KDM4EMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL10698534 | 0.76 | HTR6 (0.39) | ALDH1A1RECQL | |
| Water SCHEMBL10698996 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL9451944 | 0.70 | — | — | |
| SCHEMBL10697938 | 0.70 | TYR (0.41) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | claimed |
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |