SCHEMBL10698918

SCHEMBL10698918

CC(Cc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.34
ITGB1 P05556 2/20 0.33
ITGA4 P13612 2/20 0.33
ITGB7 P26010 2/20 0.33
DPP4 P27487 1/20 0.31
PPOX P50336 2/20 0.31
KMO O15229 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14639556 0.86 BCAT1 (0.37) FFAR4DHODH
SCHEMBL10696991 0.85 PTGS2 (0.32)
SCHEMBL9423258 0.84 DHODH (0.31) DHODH
SCHEMBL8002091 0.84
SCHEMBL10574779 0.83 PPOX (0.36) PPOXDHODH
SCHEMBL10693899 0.83 PPOX (0.31) PPOX
SCHEMBL10574871 0.82
SCHEMBL10697216 0.82 ITGB1 (0.33) ITGB1ITGA4ITGB7
SCHEMBL7256284 0.82 ICMT (0.32)
SCHEMBL4572159 0.82 PPOX (0.40) PPOXDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0255047-A1 3-Aryl uraciles and their use as herbicides CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed