Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GCK | P35557 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702652 | 0.92 | OGT (0.37) | OGTLMNAL3MBTL1MAPTGCK | |
| SCHEMBL10698492 | 0.91 | LMNA (0.36) | OGTLMNAL3MBTL1MAPTGCK | |
| SCHEMBL10699952 | 0.86 | PTGS2 (0.35) | OGTLMNAL3MBTL1MAPTGCK | |
| SCHEMBL10701638 | 0.82 | MAOB (0.32) | OGTLMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9678434 | 0.81 | PDE10A (0.39) | LMNASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL10702722 | 0.81 | ACHE (0.35) | LMNAMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10700467 | 0.81 | PDE10A (0.36) | L3MBTL1SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL10699725 | 0.80 | ATP4A (0.33) | OGTLMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10701042 | 0.79 | OGT (0.36) | OGTLMNAL3MBTL1PLGPLAU | |
| SCHEMBL10700412 | 0.78 | PLG (0.34) | OGTLMNAL3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |