Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.71 |
| ▸ | BLM | P54132 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.71 |
| ▸ | ALPL | P05186 | 2/20 | 0.71 |
| ▸ | ALPI | P09923 | 2/20 | 0.71 |
| ▸ | ALPG | P10696 | 2/20 | 0.71 |
| ▸ | GFER | P55789 | 2/20 | 0.71 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070078 | 1.00 | POLB (0.71) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL7094871 | 1.00 | POLB (0.71) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL15951399 | 0.83 | POLB (1.00) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL17548931 | 0.80 | L3MBTL1 (0.47) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL28765452 | 0.80 | L3MBTL1 (0.47) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL17548936 | 0.80 | LMNA (0.49) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL17329459 | 0.80 | L3MBTL1 (0.52) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL17329458 | 0.80 | L3MBTL1 (0.52) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL23067460 | 0.79 | POLB (0.68) | POLBBLML3MBTL1ALPLALPI | |
| SCHEMBL29557130 | 0.79 | POLB (0.68) | POLBBLML3MBTL1ALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395260-B1 | SKIN LIGHTENING COMPOSITIONS | HAARMANN & REIMER GMBH (DE) | 2002-05-28 | — | — | US | claimed |
| EP-1066821-A1 | Topical cosmetic product containing benzaldoxims | HAARMANN & REIMER GMBH (DE) | 2001-01-10 | — | — | EP | claimed |
| JP-57059810-A | — | — | None | — | — | JP | disclosed |
| JP-56057712-A | — | — | None | — | — | JP | disclosed |
| US-11759435-B2 | Dihydrochalcone derivatives influencing inflammatory states | SYMRISE AG (DE) | 2023-09-19 | — | — | US | disclosed |
| US-20220226261-A1 | DIHYDROCHALCONE DERIVATIVES INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2022-07-21 | — | — | US | disclosed |
| US-10758468-B2 | Solubilizer for cosmetic preparations | SYMRISE AG (DE) | 2020-09-01 | — | — | US | disclosed |
| EP-2633886-B1 | COMPOUNDS AND MIXTURES INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2018-01-31 | — | — | EP | disclosed |
| WO-2017186298-A1 | DIHYDROCHALCONE DERIVATIVES INFLUENCING INFLAMMATORY STATES | SYMRISE AG (DE) | 2017-11-02 | — | — | WO | disclosed |
| US-9481811-B2 | Composition and method for polishing memory hard disks exhibiting reduced edge roll-off | CABOT MICROELECTRONICS CORPORATION (US) | 2016-11-01 | — | — | US | disclosed |
| US-20160244639-A1 | COMPOSITION AND METHOD FOR POLISHING MEMORY HARD DISKS EXHIBITING REDUCED EDGE ROLL-OFF | CMC MATERIALS LLC | 2016-08-25 | — | — | US | disclosed |
| EP-1267822-A2 | USE OF 3,4-DIHYDROXY-MANDELIC ACID FOR PROTECTING AGAINST OXIDATIVE DAMAGE CAUSED BY ULTRA-VIOLET LIGHT | HAARMANN & REIMER GMBH (DE) | 2003-01-02 | — | — | EP | disclosed |
| EP-1239825-A1 | CATECHOL OXIMES AND THEIR USE IN COSMETIC AND DERMATOLOGICAL PREPARATIONS | HAARMANN & REIMER GMBH (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-6395260-B1 | SKIN LIGHTENING COMPOSITIONS | HAARMANN & REIMER GMBH (DE) | 2002-05-28 | — | — | US | disclosed |
| WO-2001098258-A1 | 3,4-DIHYDROXYMANDELIC ACID ALKYLAMIDES AND USE THEREOF | HAARMANN & REIMER GMBH (DE) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001070176-A2 | USE OF 3,4-DIHYDROXY-MANDELIC ACID FOR PROTECTING AGAINST OXIDATIVE DAMAGE CAUSED BY ULTRA-VIOLET LIGHT | HAARMANN & REIMER GMBH (DE) | 2001-09-27 | — | — | WO | disclosed |
| WO-2001043712-A1 | CATECHOL OXIMES AND THEIR USE IN COSMETIC AND DERMATOLOGICAL PREPARATIONS | HAARMANN & REIMER GMBH (DE) | 2001-06-21 | — | — | WO | disclosed |
| EP-1066821-A1 | Topical cosmetic product containing benzaldoxims | HAARMANN & REIMER GMBH (DE) | 2001-01-10 | — | — | EP | disclosed |
| JP-S5759810-A | CARCINOSTATIC AGENT | TOYOBO CO LTD | 1982-04-10 | — | — | JP | disclosed |
| JP-S5657712-A | CARCINOSTATIC AGENT | TOYOBO CO LTD | 1981-05-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10758468-B2 | Solubilizer for cosmetic preparations | SRPK3, SRPK1, SYMPK | POLB 4255/4885BLM 2047/4885L3MBTL1 2281/4885 |
| US-11759435-B2 | Dihydrochalcone derivatives influencing inflammatory states | IL17A, TNF, IL1B | POLB 2486/4885BLM 2988/4885L3MBTL1 4885/4885 |
| US-20220226261-A1 | DIHYDROCHALCONE DERIVATIVES INFLUENCING INFLAMMATORY STATES | IL17A, TNF, IL1B | POLB 2486/4885BLM 2988/4885L3MBTL1 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.