Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698492 | 0.80 | LMNA (0.36) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10702572 | 0.80 | PDE10A (0.36) | KDM4EF10L3MBTL1POLB | |
| SCHEMBL10700069 | 0.78 | LMNA (0.42) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10701035 | 0.77 | LMNA (0.40) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10700412 | 0.76 | PLG (0.34) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10700413 | 0.73 | OGT (0.36) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10702652 | 0.73 | OGT (0.37) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10702722 | 0.73 | ACHE (0.35) | MAPTLMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL9676124 | 0.71 | ATP4A (0.40) | LMNASMN1; SMN2RAB9AKDM4ENPC1 | |
| SCHEMBL10701690 | 0.71 | PRMT5 (0.36) | MAPTLMNASMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |